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These transcription factors are involved in the synthesis of several antioxidant enzymes (e.g., glutathione reductase, glutathione peroxidases, glutaredoxin, and glutathione- S -transferase), many of which are closely related to the cellular antioxidant, glutathione (Espinosa-Diez et al

Mouse embryos cultured in PF or FF from endometriosis patients show decreased cell number and rates of growth, decreased cleavage and blastulation rates, and increased rates of DNA fragmentation, developmental arrest, embryo toxicity, and apoptosis than mouse embryos cultured in PF or FF from control patients (109, 110, 135141)

In patients with myocardial infarction, NAC combined with streptokinase significantly decreased oxidative stress, improved ventricular function, and reduced acute myocardial infarction episodes

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